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2017   ​

  1. Senba M, Mori N. Challenge to the threat of invisible transmission: global health security for the control of emerging infectious disease outbreaks. In: Liang Z, Zhang B, editors. Medicine Research Summaries. Vol. 19. New York: Nova Science Publishers, 2017: 283-284.

2016   

  1. Senba M, Mori N. Challenge to the threat of invisible transmission: global health security for the control of emerging infectious disease outbreaks. In: Berhardt LV, editor. Advances in Medicine and Biology. Vol. 103. New York: Nova Science Publishers, 2016: 167-218.

  2. Senba M, Mori N. Mechanisms of cancer formation under interplay between host immunity and human papillomavirus (HPV) infection. In: Watanabe HS, editor. Horizones in Cancer Research. Vol. 61. New York: Nova Science Publishers, 2016: 19-70.

2012   

  1. Senba M, Mori N. Pathogenesis of Kaposi sarcoma associated with human herpesvirus-8 infection. In: Viktorsson K, editor. Advancements in Cancer Research. New York: Nova Science Publishers, 2012: 105-132.

2011   

  1. Senba M, Mori N, Wada A. Outbreak control for emerging, and re-emerging infectious diseases, and challenge to threat of invisible transmission. In: Alvintzi P, Eder H, editors. Crisis Management. New York: Nova Science Publishers, 2011: 159-186.

  2. Senba M, Mori N, Wada A. Oncogenesis of and the link between inflammation and cancer due to human papillomavirus (HPV) infection, and the forthcoming eradication for vaccination and the development of vaccine control strategies. In: Watanabe HS, editor. Horizons in Cancer Research. Vol. 44. New York: Nova Science Publishers, 2011: 85-115.

  3. 森　直樹: トガウイルス科・フラビウイルス科. シンプル微生物学, 東　匡伸, 小熊惠二, 堀田　博(編), 314-320, 南江堂, 東京, 2011.

Journal Publications

2024​

  1. Ishikawa C, Mori N. Pivotal role of dihydroorotate dehydrogenase as a therapeutic target in adult T-cell leukemia. Eur J Haematol, doi: 10.1111/ejh.14209. Epub ahead of print.

  2. Ishikawa C, Mori N. Inhibitory effect of a neddylation blockade on HTLV-1-infected T cells via modulation of NF-κB, AP-1, and Akt signaling. Leuk Lymphoma, doi: 10.1080/10428194.2024.2328219. Online ahead of print.

2023

  1. Ishikawa C, Mori N. Heat shock factor 1 is a promising therapeutic target against adult T-cell leukemia. Med Oncol 2023; 40: 172.

2022

  1. Ishikawa C, Mori N. Exportin-1 is critical for cell proliferation and survival in adult T cell leukemia. Invest New Drugs 2022; 40: 718-727.

  2. ​Ishikawa C, Mori N. FX1,  a BCL6 inhibitor, reactivates BCL6 target genes and suppresses HTLV-1-infected T cells. Invest New Drugs 2022; 40: 245-254. 

2021 

  1. Ishikawa C, Mori N. The antipsychotic drug pimozide is effective against human T-cell leukemia virus type 1-infected T cells. Eur J Pharmacol 2021; 908: 174373.

  2. ​Ishikawa C, Senba M, Mori N. Importin β1 regulates cell growth and survival during adult T-cell leukemia/lymphoma therapy. Invest New Drugs 2021; 39: 317-329.

  3. ​Ishikawa C, Mori N. The anti-malaria agent artesunate exhibits cytotoxic effects in primary effusion lymphoma. Invest New Drugs 2021; 39: 111-121.

2020

  1. Ishikawa C, Mori N. The role of CUDC-907, a dual phosphoinositide-3 kinase and histone deacetylase inhibitor, in inhibiting proliferation of adult T-cell leukemia. Eur J Haematol 2020; 105: 763-772. 

  2. Ishikawa C, Mori N. MALT1 as a novel therapeutic target for adult T-cell leukemia. Eur J Haematol 2020; 105: 460-467.

  3. Ishikawa C, Senba M, Mori N. Evaluation of artesunate for the treatment of adult T-cell leukemia/lymphoma. Eur J Pharmacol 2020; 872: 172953.

2018

  1. Ishikawa C, Senba M, Mori N. Anti-adult T-cell leukemia/lymphoma activity of cerdulatinib, a dual SYK/JAK kinase inhibitor. Int J Oncol 2018; 53: 1681-1690.

  2. Ishikawa C, Senba M, Mori N. Mitotic kinase PBK/TOPK as a therapeutic target for adult T-cell leukemia/lymphoma. Int J Oncol 2018; 53: 801-814. 

  3. Ishikawa C, Senba M, Mori N. Effects of NVP-BEZ235, a dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor, on HTLV-1-infected T-cell lines. Oncol Lett 2018; 15: 5311-5317.

2017   

  1. Ishikawa C, Senba M, Hashimoto T, Imaizumi A, Mori N. Expression and significance of Pim-3 kinase in adult T-cell leukemia. Eur J Haematol 2017; 99: 495-504.

  2. Ishikawa C, Mori N. In vitro and in vivo anti-primary effusion lymphoma activities of fucoidan extracted from Cladosiphon okamuranus Tokida. Oncol Rep 2017; 38: 3197-3204.

  3. Ishikawa C, Senba M, Mori N. Butein inhibits NF-κB, AP-1 and Akt activation in adult T-cell leukemia/lymphoma. Int J Oncol 2017; 51: 633-643.

2016   

  1. Ishikawa C, Jomori T, Tanaka J, Senba M, Mori N. Peridinin, a carotenoid, inhibits proliferation and survival of HTLV-1-infected T-cell lines. Int J Oncol 2016; 49: 1713-1721.

  2. Ishikawa C, Senba M, Mori N. Efficiency of AUY922 in mice with adult T-cell leukemia/lymphoma. Oncol Lett 2016; 12: 387-392.

  3. Senba M, Mori N. Oncogenesis of human papillomavirus (HPV) associated with cancers and host immune responses. Int J Cancer Res Prev 2016; 9: 1-58.

2015

  1. Ishikawa C, Senba M, Mori N. Induction of IκB-ζ by Epstein-Barr virus latent membrane protein-1 and CD30. Int J Oncol 2015; 47: 2197-2207.

  2. Ishikawa C, Senba M, Barnes BJ, Mori N. Constitutive expression of IRF-5 in HTLV-1-infected T cells. Int J Oncol 2015; 47: 361-369.

  3. Mori N, Ishikawa C, Senba M. Activation of PKC-δ in HTLV-1-infected T cells. Int J Oncol 2015; 46: 1609-1618.

2014

  1. ​Kimura R, Mori N. Abundant expression of HMGB1 in human T-cell lymphotropic virus type I-infected T-cell lines and high plasma levels of HMGB1 in patients with adult T-cell leukemia. Oncol Lett 2014; 7: 1239-1242.

2013

  1. Kimura R, Rokkaku T, Takeda S, Senba M, Mori N. Cytotoxic effects of fucoidan nanoparticles against osteosarcoma. Mar Drugs 2013; 11: 4267-4278.

  2. Mori N, Ishikawa C, Uchihara J-N, Yasumoto T. Protein phosphatase 2A as a potential target for treatment of adult T-cell leukemia. Curr Cancer Drug Tar 2013; 13: 829-842.

  3. Ishikawa C, Tanaka J, Katano H, Senba M, Mori N. Hippuristanol reduces the viability of primary effusion lymphoma cells both in vitro and in vivo. Mar Drugs 2013; 11: 3410-3424.

  4. Kimura R, Senba M, Cutler SJ, Ralph SJ, Xiao G, Mori N. Human T-cell leukemia virus type I Tax-induced IκB-ζ modulates Tax-dependent and Tax-independent gene expression in T cells. Neoplasia 2013; 15: 1110-1124. 

  5. Rokkaku T, Kimura R, Ishikawa C, Yasumoto T, Senba M, Kanaya F, Mori N. Anticancer effects of marine carotenoids, fucoxanthin and its deacetylated product, fucoxanthinol, on osteosarcoma. Int J Oncol 2013; 43: 1176-1186.

  6. Ishikawa C, Kawakami H, Uchihara J-N, Senba M, Mori N. CD69 overexpression by human T-cell leukemia virus type 1 Tax transactivation. Biochim Biophys Acta - Mol Cell Res 2013; 1833: 1542-1552.

  7. Ishikawa C, Mori N. Epstein-Barr virus latent membrane protein 1 induces CD69 expression through activation of nuclear factor-κB. Int J Oncol 2013; 42: 1786-1792.

​2012

  1. Tafuku S, Ishikawa C, Yasumoto T, Mori N. Anti-neoplastic effects of fucoxanthin and its deacetylated product, fucoxanthinol, on Burkitt’s and Hodgkin’s lymphoma cells. Oncol Rep 2012; 28: 1512-1518

  2. Tomimori K, Nakama S, Kimura R, Tamaki K, Ishikawa C, Mori N. Antitumor activity and macrophage nitric oxide producing action of medicinal herb, Crassocephalum crepidioides. BMC Complement Altern Med 2012; 12: 78.

  3. Ishikawa C, Arbiser JL, Mori N. Honokiol induces cell cycle arrest and apoptosis via inhibition of survival signals in adult T-cell leukemia. Biochim Biophys Acta – Gen Subjects 2012; 1820: 879-887. 

  4. Nakama S, Tamaki K, Ishikawa C, Tadano M, Mori N. Efficacy of Bidens pilosa extract against herpes simplex virus infection in vitro and in vivo. Evid Based Complement Alternat Med 2012; 2012: 413453.

  5. Mori N, Nakasone K, Tomimori K, Ishikawa C. Beneficial effects of fucoidan in patients with chronic hepatitis C virus infection. World J Gastroenterol 2012; 18: 2225-2230.

  6. Tomita M, Tanaka Y, Mori N. MicroRNA miR-146a is induced by HTLV-1 Tax and increases the growth of HTLV-1-infected T-cells. Int J Cancer 2012; 130: 2300-2309.

  7. Ishitsuka K, Kunami N, Katsuya H, Nogami R, Ishikawa C, Yotsumoto F, Tanji H, Mori N, Takeshita M, Miyamoto S, Tamura K. Targeting Bcl-2 family proteins in adult T-cell leukemia/lymphoma: in vitro and in vivo effects of the novel Bcl-2 family inhibitor ABT-737. Cancer Lett 2012; 317: 218-225.

  8. Takeda K, Tomimori K, Kimura R, Ishikawa C, Nowling TK, Mori N. Anti-tumor activity of fucoidan is mediated by nitric oxide released from macrophages. Int J Oncol 2012; 40: 251-260.

  9. Senba M, Kawai K, Mori N. Pathogenesis of metastatic calcification and acute pancreatitis in adult T-cell leukemia under hypercalcemic state. Leuk Res Treatment 2012; 2012: 128617.

  10. Senba M, Mori N. Mechanisms of virus immune evasion lead to development from chronic inflammation to cancer formation associated with human papillomavirus infection. Oncol Rev 2012; 6: e17.

​2011

  1. Nakayama Y, Ishikawa C, Tamaki K, Fujita J, Mori N. Interleukin-1α produced by human T-cell leukemia virus type I-infected T cells induces ICAM-1 expression on lung epithelial cells. J Med Microbiol 2011; 60: 1750-1761.

  2. Kimura R, Ishikawa C, Rokkaku T, Janknecht R, Mori N. Phosphorylated c-Jun and Fra-1 induce matrix metalloproteinase-1 and thereby regulate invasion activity of 143B osteosarcoma cells. Biochim Biophys Acta - Mol Cell Res 2011; 1813: 1543-1553.

  3. Senba M, Buziba N, Mori N, Morimoto K, Nakamura T. Increased prevalence of Kaposi’s sarcoma-associated herpesvirus in the Kaposi sarcoma-endemic area of Western Kenya in 1981-2000. Acta Virol 2011; 55: 161-164.

  4. Mori N, Ishikawa C, Senba M. Induction of CD69 expression by cagPAI-positive Helicobacter pylori infection. World J Gastroenterol 2011; 17: 3691-3699.

  5. Mori N, Ishikawa C, Senba M, Kimura M, Okano Y. Effects of AZD1152, a selective Aurora B kinase inhibitor, on Burkitt’s and Hodgkin’s lymphoma. Biochem Pharmacol 2011; 81: 1106-1115.

  6. Nakama S, Ishikawa C, Nakachi S, Mori N. Anti-adult T-cell leukemia effects of Bidens pilosa. Int J Oncol 2011; 38: 1163-1173.

  7. Nakachi S, Nakazato T, Ishikawa C, Sawada S, Kimura R, Mann DA, Senba M, Masuzaki H, Mori N. Human T-cell leukemia virus type 1 Tax transactivates the matrix metalloproteinase 7 gene via JunD/AP-1 signaling. Biochim Biophys Acta - Mol Cell Res 2011; 1813: 731-741.

  8. Araya N, Takahashi K, Sato T, Nakamura T, Sawa C, Hasegawa D, Ando H, Aratani S, Yagishita N, Fujii R, Oka H, Nishioka K, Nakajima T, Mori N, Yamano Y. Fucoidan therapy decreases the proviral load in patients with human T-lymphotropic virus type 1-associated neurological disease. Antivir Ther 2011; 16: 89-98.

  9. Hasegawa H, Yamada Y, Tsukasaki K, Mori N, Tsuruda K, Sasaki D, Usui T, Osaka A, Atogami S, Ishikawa C, Machijima Y, Sawada S, Hayashi T, Miyazaki Y, Kamihira S. LBH589, a deacetylase inhibitor, induces apoptosis in adult T-cell leukemia/lymphoma cells via activation of a novel RAIDD-caspase-2 pathway. Leukemia 2011; 25: 575-587.

  10. Tsumuraya T, Ishikawa C, Machijima Y, Nakachi S, Senba M, Tanaka J, Mori N. Effects of hippuristanol, an inhibitor of eIF4A, on adult T-cell leukemia. Biochem Pharmacol 2011; 81: 713-722.

  11. Fu J, Qu Z, Yan P, Ishikawa C, Aqelian RI, Rabson AB, Xiao G. The tumor suppressor gene WWOX links the canonical and non-canonical NF-κB pathways in HTLV-I Tax-mediated tumorigenesis. Blood 2011; 117: 1652-1661.

  12. Yamamoto K, Ishikawa C, Katano H, Yasumoto T, Mori N. Fucoxanthin and its deacetylated product, fucoxanthinol, induce apoptosis of primary effusion lymphomas. Cancer Lett 2011; 300: 225-234.

  13. Ishikawa C, Nakachi S, Senba M, Sugai M, Mori N. Activation of AID by human T-cell leukemia virus Tax oncoprotein and the possible role of its constitutive expression in ATL genesis. Carcinogenesis 2011; 32: 110-119.

  14. Senba M, Buziba N, Mori N, Fujita S, Morimoto K, Wada A, Toriyama K. Human papillomavirus infection induces NF-κB activation in cervical cancer: a comparison with penile cancer. Oncol Lett 2011; 2: 65-68.

  15. Senba M, Mori N. Pathogenesis of Kaposi sarcoma associated with human herpesvirus-8 infection. Cancer Res J 2011; 4: 101-128.

Academic Publications 

- Albert Einstein -

“In the middle of difficulty lies opportunity”

PUBLICATIONS

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